Patient: A lump was found in the middle of the sublingual area and was diagnosed as highly differentiated squamous cell carcinoma with signs of bleeding and loosening of two surrounding teeth. A small foreign body was found under the tongue in about October, which was not a concern at that time. On January 23, 2009, I underwent partial excision of sublingual and mandibular lymphatic excision, and 10 points of pathology around the lesion were taken. What is the best treatment plan to prevent recurrence after surgery for this condition? How long after discharge from the hospital should I receive radiotherapy or chemotherapy? Highly differentiated squamous cell carcinoma has been discharged from the hospital after surgery. The treatment of squamous cell carcinoma at the floor of the mouth is a comprehensive treatment mainly based on radical resection by surgery. For T1 and T2 patients, postoperative radiotherapy or chemotherapy is not necessary for those with complete lesion excision. Due to the high rate of cervical lymphatic metastasis in basilar carcinoma, elective neck clearance is usually required. For highly differentiated squamous carcinoma, radiotherapy and chemotherapy are not very sensitive. Please communicate more with the operator to determine the next treatment plan.