A bump in the trachea may be a neoplasm, more commonly including granulomatous disease or malignant tumors. Granulomatous disease in the trachea is usually associated with infection. Infections are commonly caused by Mycobacterium tuberculosis, which causes endobronchial tuberculosis and tuberculous granulomas, which appear as elevations of the trachea or bronchial lining, forming small bump-like changes. If it is caused by Mycobacterium tuberculosis infection, anti-tuberculosis treatment, such as isoniazid, rifampicin and other drugs, needs to be given. Small bumps in the trachea may also be malignant tumors, such as lung cancer. Early stage lung cancer usually manifests as submucosal elevation of trachea-bronchus, which is manifested as small lumps. Fiberoptic bronchoscopy can be used to take specimens for biopsy, and if it is clear that it is malignant in nature, surgical resection or radiotherapy and other treatments need to be taken in time. A small lump in the trachea may also be caused by other reasons, such as chronic inflammation. It is recommended to consult a doctor in time, according to the doctor’s instructions for further examination and treatment, to avoid delaying the condition.