Waking up with stomach pain is related to improper diet, chronic gastritis, duodenal ulcer and other factors. Many people will have improper eating habits and often eat foods that are difficult to digest at night, such as grilled meat and iced drinks, which will not only cause irritation to the gastrointestinal mucosa, but also increase the burden on the digestive system. Going to bed after consuming a large amount of such food will lead to an increased burden on the digestive system. As a result, after waking up, the digestive system is overworked and the stomach feels distended. Patients with chronic gastritis have a chronic progression of the disease, which is manifested by pain in the stomach during an attack, and the pain is irregular, and many patients will wake up with an attack of the disease and therefore experience pain in the stomach. Patients with duodenal ulcer will have hunger pains, and most people are hungry in the morning when they wake up. At this time, stomach acid in the stomach, in a high-intensity state, will enter the duodenum, causing an invasion of the ulcerated surface of the duodenal mucosa, and therefore causing stomach pain.