The skin is very dry and rough may be related to the lack of vitamin A, B2, E, etc. Secondly, the skin is very dry and rough may also be caused by physiological factors such as skin dehydration, or dry eczema, atopic dermatitis and other diseases. 1. Lack of vitamins: if the body lacks vitamin A, B2, E, etc., may trigger the skin to appear dry and rough. 2. Physiological factors: Skin dehydration, dry climate and other physiological factors may also trigger the symptoms of very dry and rough skin. 3. Dry eczema: its cause may be related to the reduction of oil, skin aging, habitual rubbing and other factors. Patients will have dry, cracked skin, as well as flaking, rough and other symptoms. 4. Atopic dermatitis: its cause may be genetic, immune abnormalities, environment, dysbiosis and skin barrier function abnormalities and other factors. The patient will have dry, rough skin as well as erythema, papules, intense itching and other symptoms. Very dry and rough skin may be related to vitamin deficiency, but it may also be caused by other reasons. After excluding physiological factors, patients are advised to seek medical examination to clarify the cause.