Colon cancer metastasis to one side of the ovary for is stage IV. After colon cancer cancer cells are planted through the abdominal cavity and ovarian metastasis occurs, it indicates that the cancer has reached stage IV, which is an advanced stage. When colon cancer generally has ovarian metastasis on one side, surgical resection, prophylactic ovariectomy, supplemented by radiation therapy and medication can help patients to relieve and control symptoms. Commonly used drugs include fluorouracil and oxaliplatin. Resection of both adnexa is recommended for all patients with definite ovarian metastases. For patients with extensive metastasis, tumor reduction surgery together with radiotherapy can prolong the survival period and improve the quality of patient’s life. If colon cancer metastasizes to one side of ovary, one should consult doctor in time and follow the standardized treatment.