Entecavir is mainly metabolized by the kidneys, and long-term use may cause glomerular injury secondary to changes in renal function.
Entecavir is an antiviral drug that is mainly metabolized by the kidneys and can undergo two processes of glomerular filtration and tubular secretion. If the medication is used for too long a period of time and at too high a dose, it may damage the glomeruli and tubules, thus reducing renal function and, in severe cases, leading to renal insufficiency.
Entecavir is mainly used for the treatment of chronic hepatitis B virus infection, renal insufficiency need to adjust the dosage in the process of use, but in the process of use may occur headache, diarrhea, insomnia and other adverse reactions, and in the process of use should pay attention to monitor liver and kidney function.
Entecavir should be used under the guidance of a doctor, and timely monitoring of kidney function, if abnormalities occur, should be timely regular hospital medical care.