Papular urticaria is an allergic skin disease that is more common clinically and is associated with both mosquito and insect bites. The skin reacts allergically to mosquito venom, resulting in red papules on the skin, papules with significant itching. It occurs mainly in exposed areas, such as the lower legs and ankles. Papular urticaria has been recurring, and mosquito bites or repeated scratching have a certain relationship. To avoid recurrence must kill mosquitoes, and then there to avoid scratching stimulation. At the same time to actively cooperate with the treatment, you can take oral antihistamine drugs, local can be applied topical hormone cream to strengthen the anti-inflammatory effect. Some patients local scratching after the occurrence of infection, this time to strengthen the anti-bacterial treatment, you can also apply topical fusidic acid or mupirocin cream, etc..