Hepatitis B surface antigen greater than 250ng/ml is hepatitis B surface antigen positive, indicating that the subject has hepatitis B virus in the body. Hepatitis B surface antigen (HBsAg) positive, the patient may be acute and chronic hepatitis B virus infection or chronic carriers HBsAg carriers, need to determine the specific situation through the results of hepatitis B five tests. 1. If Hepatitis B surface antigen and Hepatitis B core antibody are positive, it means that the patient may have acute hepatitis B virus infection or chronic HBsAg carrier. 2. If Hepatitis B surface antigen, Hepatitis B core antibody and e antibody are positive, it means that the patient may be recovering from acute Hepatitis B virus infection or chronic HBsAg carriers. 3. If hepatitis B surface antigen, hepatitis B core antibody and e antigen are positive, it indicates acute and chronic hepatitis B virus infection, and the result suggests that HBV is highly replicated and infectious. Patients found that hepatitis B surface antigen is greater than 250ng/ml should go to the hospital in time, follow the doctor’s instructions for standardized treatment.