Both bivalirudin and erliximab can be used for the treatment of osteoarthritis, the specific therapeutic effect varies from person to person, and it is impossible to accurately judge who is better. Bivalirudin belongs to interleukin-1 receptor inhibitor, suitable for the treatment of osteoarthritis of hip and knee joints. It should be contraindicated in people who are allergic to the product or to anthraquinone derivatives, people with unexplained abdominal pain, people with intestinal obstruction or pseudo-obstruction, people with inflammatory bowel disease, and people with hereditary lactose intolerance. The most common adverse reactions are abdominal pain, diarrhea, frequent bowel movements, and flatulence. Note: Bisacodyl should be avoided when taken with laxatives. Erythroxib belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and is indicated for the pain relief treatment of osteoarthritis. Common adverse drug reactions following administration include epigastric discomfort, fecal occult blood, and elevated alanine aminotransferase. It should be contraindicated in persons who are hypersensitive to this product, other xibutans or sulfonamides, persons with severe heart failure, persons requiring perioperative pain management for coronary artery bypass grafting surgery, persons who are hypersensitive to or have a history of gastrointestinal bleeding or perforation following administration of NSAIDs, and persons with previous or current active peptic ulcers or bleeding. Note: This product may cause new onset of hypertension or aggravate symptoms of pre-existing hypertension. Both bisacodyl and erliximab have certain therapeutic effects on osteoarthritis, but it is not possible to state clearly whose therapeutic effect is better, mainly because there is individual variability in the group of people who use the medication, and the effect of the medication is different, so it is not possible to compare whose effect is better. The specific use of drugs should be carried out under the guidance of a specialist, not unauthorized use of drugs.