Early symptoms of dry syndrome are varied, and dry mouth and dry eyes are the most common. 1. Dry syndrome is a systemic autoimmune disease that mainly involves exocrine glands. In addition to exocrine glands, it also involves organs of the whole body. 2. Therefore, different clinical symptoms may appear depending on the organs involved, but most of the patients with dry syndrome still have dry mouth and dry eyes as the main early clinical symptoms. 3. In some patients, skin and joints are involved, and early symptoms include skin rash, joint swelling and pain. A few patients may directly take the damage of organs as the early clinical symptoms, such as coughing and phlegm shortness of breath in the lungs, and low potassium and proteinuria in the kidneys. If symptoms such as dry mouth and eyes, skin rash and joint pain occur, it is necessary to go to the rheumatology department of the hospital for prompt diagnosis and standardized treatment.