There is no most effective treatment for cough and phlegm. Cough and sputum need to be treated according to the cause of the disease, common diseases such as common cold, tuberculosis, chronic bronchitis, etc., can be improved through general treatment, medication and other ways to improve the symptoms. 1. Common cold: Mostly caused by viral infection, coughing and sputum may appear. It is recommended that patients take proper rest, drink more water and pay attention to oral and nasal hygiene. If the amount of sputum is small, cough suppressants such as codeine and dextromethorphan can be used to reduce coughing symptoms; if the sputum is large and not easy to cough up, cough suppressants and expectorants such as bromhexine, aminoglutethimide and acetylcysteine can be used to relieve symptoms. 2. Tuberculosis: This disease is also one of the causes of cough and sputum, and may have fever, night sweats and other symptoms. Anti-tuberculosis drugs such as isoniazid, rifampicin and pyrazinamide can be used for treatment. 3. Chronic bronchitis: the most important symptoms are chronic cough and sputum. In the stabilization period, the main focus is to quit smoking, pay attention to warmth, and prevent infection. If the acute exacerbation period, the first active anti-infection treatment, such as the use of levofloxacin, amoxicillin and other drugs. Cough and sputum can be relieved by coughing and expectorant drugs such as compound licorice, bromhexine, and ambroxol hydrochloride. Cough and sputum can also be caused by a variety of other diseases, if the symptoms are not relieved or aggravated, it is recommended to consult a doctor in a timely manner, improve the examination, to clarify the cause of the disease, and standardize the treatment under the guidance of the doctor, so as to avoid delaying the condition.