Quick pain relief for peri-shoulder pain needs to be based on the cause of the disease to take treatment, generally there are rest, physical therapy, drugs and surgical treatment and other methods. 1. Physiological reasons: such as overwork or excessive exercise leads to lactic acid and other metabolites accumulation in the periapical muscles, patients can have periapical pain, fast pain relief can take rest, hot compresses and other physical therapy methods, if necessary, you can use ibuprofen and other painkillers to relieve pain. 2. Trauma: due to collision, fall and other traumatic injuries, patients may suffer from shoulder fracture, dislocation and surrounding soft tissue injury, which may cause peri-shoulder pain. If the injury is mild, shoulder joint braking, early cold compresses and painkillers such as ibuprofen can be taken to relieve pain. If the injury is severe, in addition to the above treatments, the patient needs to consult the hospital in time and take surgical treatment if necessary in order to completely relieve pain. 3. Frozen shoulder: due to various reasons of aseptic inflammation of the soft tissues around the shoulder joint, the pain around the shoulder can be caused by rest, cold compresses in the acute stage, painkillers such as Etoricoxib, and local closure can be taken for pain relief treatment if necessary. 4. Shoulder joint disease: If the pain is caused by shoulder arthritis, shoulder tumor, etc., rest, etoricoxib, ibuprofen and other painkillers can be taken in the acute stage, but if you want to solve the problem completely, you need to clarify the specific cause of the disease and then take treatment. Patients with peri-shoulder pain are advised to consult a doctor in a timely manner to clarify the cause of the disease and choose the appropriate method of treatment with the help of the doctor. The above drugs should be used under the guidance of a doctor, avoid self-medication.