Delayed menstruation at the age of 50 may be caused by a decline in ovarian function and low estrogen production. However, the possibility of pregnancy cannot be ruled out even in a 50-year-old woman, so it is important to actively look for the cause. An ultrasound can be performed to check the condition of the endometrium and adnexa, and a blood HCG test can be performed to rule out pregnancy as the cause of delayed menstruation. If it is not caused by pregnancy, most of the time it is caused by the decline of ovarian function. Because this is the perimenopausal period, irregular menstruation is a normal physiological phenomenon. Therefore, if there is no special discomfort, it can be left untreated for the time being for observation. If perimenopausal syndromes occur, such as hot flashes, night sweats, irritability, etc., hormone replacement therapy can be given to relieve the symptoms of menopause if there are no contraindications to taking medication after a health checkup.