Physiological male nipple depression does not need treatment, inflammation, tumors and other diseases caused by nipple depression, go with the doctor to receive medication surgery and other treatments. 1. Physiological: some men’s nipple depression is related to congenital genetic factors. If there are no obvious clinical symptoms and physical discomfort, there is no need to receive treatment for the time being. If the depression is serious, it needs to be treated in order to prevent it from causing mastitis and other diseases. 2. Inflammation: If you don’t pay attention to personal hygiene, you will easily suffer from mastitis when your resistance is low, leading to nipple inversion. At this time, you need to follow the doctor’s instructions to use antibiotics, such as cefuroxime, levofloxacin, etc., in order to control the inflammatory reaction. 3. Tumor: malignant tissues of male breast cancer can also cause nipple inversion by pulling the skin muscle. In this case, according to the stage of the disease, it is necessary to receive comprehensive treatment such as surgery, radiotherapy, chemotherapy, etc., in order to improve the situation of nipple concavity. There may be other causes of nipple inversion in men. It is recommended to go to the breast surgery department of the hospital to take the appropriate treatment plan according to the specific condition of the patient.