The most effective drugs for insomnia are now sleeping pills, which are the largest and most dominant drugs. Sleeping pills generally act on GABA receptors in the brain and are dominated by benzodiazepine inhibitors, including some of the newer, selective benzodiazepine inhibitors. All drugs that act on GABA receptors carry the risk of dependence with long-term use. This class of drugs is characterized by very fast and definite efficacy, and one can definitely fall asleep once taken. Its adverse effects and disadvantages are dependence with long-term use. The main manifestations of dependence are: one is tolerance, that is, I may take half a capsule on the line, but I may have to take one or even two capsules to achieve that effect; the second is the phase reaction, that is, if I suddenly stop taking it one day, I may not be able to sleep at all this day, this is the advantage and disadvantage of benzodiazepines; there is also a class of drugs with sedative effect of anti-anxiety drugs, such as tricyclic Antidepressants, chlorpromazine, for example, trazodone, or mirtazapine, these are commonly used anti-anxiety, antidepressants, also have a better sleep effect, the characteristics of these drugs is not fast-acting, not eat ten minutes immediately fall asleep, but it is not dependent, which is very important for patients. There is also a large category of antipsychotic drugs with strong sedative effects, many patients are afraid to take these drugs, he said how the doctor prescribed me antipsychotic drugs? In fact, all antipsychotic drugs have a good sedative effect when used in small doses, and there is no risk of dependence, and the impact on cognitive function is relatively mild, so it is also a major clinical choice; others are some health products with sedative effects, such as melatonin, paracetamol – a blocker of H1 receptors, which is a cold medicine, after taking It will also be drowsy, because the main drug in it is the blocker of H1 receptors – paracetamol. In addition, there are some anti-allergy drugs, such as cycloheximide, have a better sedative effect.