The formula of Pu Huang and Wu Ling Zhi is commonly used as the Chinese herbal formula Lost Smile San, and the specific time of taking it should be decided by a Chinese medicine practitioner according to the condition of the patient. Lost Smile San, made of fried Pu Huang and Wu Ling Zhi, has the effect of activating blood circulation and removing blood stasis (promoting blood circulation and eliminating blood stasis in the body), dispersing knots and relieving pain, and it can treat all the symptoms caused by blood stasis and stagnation, and it is effective in treating menstrual disorders, dysmenorrhea, tingling pain in the epigastric region, aggravated by nightfall, and purplish and dark tongue, etc. In the formula, Wu Ling Zhi enters the liver meridian and blood division (the four components of warm disease, Wei Qi and Ying Blood). The formula in the five spirit fat into the liver meridian blood (in the warm disease Wei Qi Ying blood four periods, belong to the most in-depth stage or disease), can be through the blood, blood stasis pain; Pu Huang can line the blood to eliminate blood stasis, fried also can stop bleeding, the two medicines with, for the activation of blood circulation and eliminate blood stasis, the common basis of the knot pain, medicine simple effect macro. The medication is usually taken while the disease is still in progress (for drugs with strong medicinal properties, the medication should be stopped after the disease is generally cured to avoid damage), the specific time of taking the medication should be decided by a Chinese medicine practitioner according to the condition of the patient, do not stop taking the medication or prolong the time of taking the medication on your own, and it is recommended that if you feel unwell during the course of taking the medication, you should consult a doctor in a timely manner.