Coronary heart disease into the stent after the need for long-term drug nitrate drugs, anticoagulant, antiplatelet drugs, lipid regulating drugs, beta-blockers and other drugs, specific need to combine with the patient’s condition comprehensive judgment. 1. Nitrate drugs: can expand the coronary artery to relieve myocardial ischemia, improve the blood supply of heart circulation. Representative drugs are nitroglycerin, isosorbide mononitrate and so on. 2. Anticoagulant and antiplatelet drugs: they can inhibit the activity of coagulation factors and reduce platelet aggregation to prevent thrombosis and the progress of existing thrombus. Representative drugs are warfarin, aspirin and so on. 3. Lipid-regulating drugs: they can regulate the level of blood lipids, control it within the normal range and prevent the formation and progress of atherosclerosis. The representative drugs are atorvastatin, fenofibrate and so on. 4. β-blocker: it can inhibit myocardial β-receptor, slow down the heart rate and weaken myocardial contractility, reduce myocardial oxygen consumption. Representative drugs are propranolol, metoprolol and so on. Coronary stent implantation has the possibility of restenosis and re-infarction, patients must be under the guidance of specialists, adhere to the medication to avoid adverse consequences.