The causes of menstrual migraines are mainly related to hormonal changes, and can be treated with painkillers and antiemetic and sedative drugs, as well as psychotherapy. 1. Causes Menstrual migraine may be related to hormonal changes. Before and after menstruation, the concentration of estradiol in the blood decreases, causing intracranial and extracranial blood vessels to be more sensitive to substances such as 5-hydroxytryptamine, which causes changes in vascular tone. People with sensitive body may thus trigger migraine. 2. Treatment (1) Pain medication: For mild symptoms, ibuprofen, aspirin, diclofenac, naproxen and other medications can be used. If it belongs to moderate – severe headache and lasts for a long time, it can be treated with ergotamine caffeine combination. (2) Antiemetic and sedative drugs: antiemetic drugs such as metoclopramide and domperidone can improve the symptoms of nausea and vomiting in patients with migraine; benzodiazepines and barbiturates can induce patients to be sedated, sleep, and promote the disappearance of headache. (3) Psychotherapy: Behavioral therapy can make patients relax and correctly perceive the disease, or through cognitive therapy, correctly deal with the stress reaction or reduce the triggering factors. Patients with menstrual migraine should consult a doctor in time and receive reasonable treatment under the doctor’s guidance. Avoiding foods such as cheese, coffee and red wine will help the recovery of the condition.