Antipyretic suppositories and Merrill Lynch can be used interchangeably. However, simultaneous use is not recommended. Merrill refers to ibuprofen. Fever reducer contains acetaminophen, acetaminophen and ibuprofen belong to the non-steroidal anti-inflammatory drugs, both have the effect of antipyretic and analgesic, the two can not be used together, because the efficacy of the drug will not have a significant increase in the side effects will be superimposed. Acetaminophen reduces prostaglandin synthesis, making the body insensitive to pain-causing substances to achieve analgesia, and changes the thermoregulatory center to play the role of antipyretic. Ibuprofen is also a non-selective cyclooxygenase inhibitor, mainly through the inhibition of the cyclooxygenase enzyme to inhibit the production of prostaglandins, resulting in significant anti-inflammatory, antipyretic and analgesic effects. Acetaminophen can cause nausea, vomiting, anemia and other adverse reactions, allergy to this drug or renal insufficiency is prohibited. Ibuprofen can cause nausea, stomach bleeding, headache and other adverse reactions, allergic to this drug and pregnant women are prohibited. If you are not feeling well, do not take the medicine by yourself, go to the hospital and take the medicine under the doctor’s guidance, so as not to delay the condition or have adverse reactions.