Creatine kinase 280 U/L is considered elevated and can be seen in muscle injury, myocardial infarction, and other conditions. The normal value of creatine kinase is 40-200 U/L, and different manufacturers’ reagents may have slightly different standards. Creatine kinase is mainly located in the mitochondria, closely related to the generation of ATP in the body, is an important enzyme in the metabolism of the body, the normal range is 40-200U / L, but different manufacturers of the actual reference range of different ages have some differences. Elevated creatine kinase is closely related to muscle injury, which can be seen in rhabdomyolysis, mostly manifested as elevated creatine kinase, and patients may manifest myalgia. Patients with myocardial infarction tend to have both elevated creatine kinase and isoenzyme. Patients with elevated creatine kinase should pay attention to understand the patient’s, if there are symptoms of acute pain chest pain, should promptly go to the hospital.