The widespread use of antipsychotic drugs since the 1950s has led to significant improvements in the treatment of schizophrenia, which are mainly reflected in improved treatment outcomes, shorter treatment courses, and greatly improved social adjustment of psychiatric patients. Antipsychotic drugs are currently the main treatment for schizophrenia and also serve as the basis for other complementary treatments. The availability of drugs can only affect the course of the disease to a certain extent, but they fail to remove the root cause of the disease. Therefore, the nature of the action of such medications also determines the long-term nature of treatment, which means that patients must be given longer maintenance and consolidation therapy after a period of adequate treatment in order to ensure stability and reduce relapse. Antipsychotic drugs have a significant effect on the treatment of schizophrenia, but this treatment is symptomatic. Therefore, they are prone to relapse after discontinuation, and the longer the time off medication, the greater the likelihood of relapse. One study showed that 4 weeks after stopping medication, there was a 25% chance of relapse, six months after stopping medication it was 51% to 75%, and 1 year after stopping medication there was a 73% to 85.4% chance of relapse. A study was done abroad, in which 1018 people were not given maintenance treatment, resulting in 698 relapses, with a relapse rate of 65%, while 2127 cases were treated with antipsychotics for consolidation, with only 639 relapses, with a relapse rate of only 30%. The above figures show that there is at least a 2-fold difference in the relapse rate between maintenance with medication and consolidation without medication. It can be argued that medication maintenance has a significant relapse prevention effect. Under the premise that there is no cure for schizophrenia at the moment, in order for more patients to return to society, go on to a colorful life, and regain their former laughter, please heed the heartfelt advice of mental health care workers: maintenance treatment should be adhered to. Some people may also ask: Why do many advertisements in society claim to be able to cure or cure mental illness? Why are there some psychiatric patients who do not relapse after treatment? Will taking medication for a long time have any effect on the body? And so on. We can responsibly say that the so-called cure and cure for mental illness is a deceptive propaganda, the effect achieved by their treatment is only a temporary improvement, not the real root. There is no scientific basis to prove that a cure for mental illness can be achieved. We have seen many gullible people who have been deceived and regret it. Of course, there is no denying that some patients do not relapse for life after regular treatment, and this percentage is about 20%. However, this relapse is not the result of a certain drug or therapy, but the disease itself. As for the impact of prolonged medication on the body, the answer is yes, everything must be seen in its main aspects, the benefits of maintenance therapy for patients always outweigh the impact of side effects on the body, moreover, under the guidance of a specialist to properly control the dose of maintenance therapy, both to effectively prevent relapse and to control the side effects of drugs to a minimum. Moreover, some of the latest new drugs listed have greatly reduced side effects, and some of them have a protective effect on the brain when taken for a long time. Because the exact cause of relapse is unknown and the treatment of psychosis is limited, maintenance treatment is necessary only in terms of its general trend.