The male urethra pus urine sting may be gonorrhea urethritis, non-gonococcal urethritis, prostatitis and other conditions caused by its seriousness need to be judged according to the patient’s specific situation. 1. usually gonococcal urethritis can be given doxycycline, levofloxacin, etc., gonococcal urethritis in the acute phase of timely and regular treatment can be completely cured. If the treatment is untimely or incomplete, complications can arise, such as infertility, urethral stenosis and so on. It will also increase the psychological and physiological pain to the patient, the situation is relatively serious. 2. non-gonococcal urethritis according to the pathogen to choose antibiotics, commonly used drugs include azithromycin, erythromycin, etc., timely and active treatment can be cured, most of the patients have a better prognosis, generally not serious. 3. Prostatitis: generally acute and chronic bacterial prostatitis prognosis is better, most patients in the active treatment can be cured, a very small number of patients can be complicated by prostate abscess, but after incision and drainage surgery can also be cured, generally not serious. It is recommended that when a man is experiencing urethral pus and pain in the urine, he should determine whether it is serious or not according to his own situation, and then consult a doctor for targeted treatment in a timely manner.