Hypokalemia has different clinical manifestations due to the different speed and degree of reduction of blood potassium, and may have effects on the neuromuscular system, cardiovascular system, digestive system and so on. 1. Influence of neuromuscular system: Hypokalemia can lead to reduction of excitability of nerves and muscles, in mild cases, there are no symptoms or only fatigue and general weakness, in severe cases, flaccid paralysis of lower limbs can occur, and in serious cases, it can involve upper limbs, trunk and respiratory muscles. 2. Impact on cardiovascular system: Hypokalemia can lead to increased myocardial excitability and autoregulation, which may lead to atrial flutter, supraventricular tachycardia and other arrhythmic manifestations, and may also lead to panic, chest tightness, drop in blood pressure and heart failure. 3. Impact on digestive system: Hypokalemia can lead to decreased excitability of smooth muscle, weakening of gastrointestinal function, nausea, vomiting, abdominal distension, loss of appetite and other manifestations, and paralytic intestinal obstruction can occur in severe cases. Hypokalemia also affects the kidneys and central nervous system, resulting in polyuria, low specific gravity urine, depression, drowsiness and other clinical manifestations. It is recommended that the patient should consult the doctor in time and receive proper treatment under the doctor’s guidance.