In China, the total prevalence of chronic kidney disease is about 9.3%, of which 1% may develop into uremia. Kidney transplantation is currently the treatment of choice for UTI, and the shortage of donors is a worldwide problem, making living kidney transplantation an important channel to provide donors. Recent research and clinical findings show that the success rate of organ transplantation between husband and wife among relative kidney donors is high, with little or no immune rejection. On the eve of Valentine’s Day this year, the renal transplantation department of Lingnan Hospital, the third hospital affiliated to Sun Yat-sen University, completed such a transplantation, with the 47-year-old wife donating her left kidney to her 49-year-old husband who suffered from uremia, and the couple was successfully discharged from the hospital a few days ago. Couples for many years, post-operative rejection reaction is small Last November, the body has always been good 49-year-old Mr. Liu found that recently his feet edema, and also weight from the previous 180 pounds quickly dropped to 120 pounds, to go to the hospital for examination, the results were diagnosed with uremia. This disease requires long-term dialysis to maintain life, Mr. Liu in the treatment process of physical and mental torture, such as patients have to strictly control water, Mr. Liu’s several patients can not properly control the water and lead to acute heart failure attack passed away. Finally, Mr. Liu’s wife, 47-year-old Ms. Chen, offered to donate one of her kidneys to her husband. Before the surgery, both the kidney organ donor and recipient should be mated and examined for various body indicators, and as a result, Mr. Liu’s blood type is the same as type A for both husband and wife, and both mates are suitable for the surgery. After the surgery, Mr. Liu’s kidney function had dropped to the normal range and could be treated without dialysis. Professor Sun Qiquan, director of the renal transplantation department of Lingnan Hospital, the third hospital affiliated to Sun Yat-sen University, said that the rejection after kidney transplantation is a key point affecting the effect of surgery, and Mr. Liu and his wife, who have lived together for many years, had very little rejection after surgery, and the husband’s body is recovering well. The transplant effect is second only to the identical twin donor kidney According to the introduction, China has become the second largest organ transplant country after the United States. According to the Ministry of Health statistics, about 1.5 million people need organ transplants in China every year, but only 10,000 people can receive transplants, the contradiction between the supply and demand of organs is very prominent. Ten years ago, domestic experts, drawing on the new tendencies of Japan, Taiwan and Hong Kong, successively proposed two strategies to solve the problem of organ sources – intra-family self-help and multi-family mutual help, which means living organ transplantation. Under the current severe organ shortage, kidney donation by relatives is a last resort, but it is also an important source of kidney transplants at home and abroad, said Sun Qiquan. “In the United States, nearly half of the kidney donations come from relatives, and in Japan, almost all of the kidney transplants are from relatives. The effect of transplantation is better than that of cadaveric kidney because of the good mating, short ischemic time and good quality of kidney donor, and the effect of transplantation between husband and wife is even better than that of sibling kidney donor because of long-term living together, which is called ’emotional kidney’,” said Sun Qiquan. Sun Qiquan said. Of course the effect of an inter-identical twin donor kidney is still the best, with no need for anti-rejection drugs at all, but this is a rare occurrence. Now there are studies that show that organ transplants between couples, almost no immune rejection or very mild, this is because of the long-term intimate contact between the couple, will continue to exchange a small amount of antigens, so the generation of immune tolerance. Especially when the wife is pregnant, the antigens of the husband pass through the placenta and enter the uterus. This is why organ transplantation between husband and wife is less likely to result in rejection. Therefore, there is a medical reason for the common saying “husband and wife”. It is important to note that living transplantation may affect the health of the donor, so a systematic assessment of the donor’s health condition is needed to keep the effects within acceptable limits. In addition, because the blood vessels of the living donor kidney are very short, the surgery is difficult, because patients are advised to always choose a hospital with strong technical conditions for the surgery. Here, we still advocate the call for “organ donation after the death of a citizen” to help solve the long-term problem of organ transplantation. ”Emotional kidney” donation has conditions According to the former Ministry of Health “Human Organ Transplantation Regulations”, organ transplantation first meets certain conditions of ethical principles, such as donating human organs should be on a voluntary and non-remunerated basis, while the recipient of living organs is limited to the spouse of the living organ donor, blood relatives in the direct line or collateral blood relatives within three generations, must The couple must have been married for at least 3 years. The procedure must also be reviewed and approved by the provincial health department. Secondly, it also depends on whether the medical conditions are met, such as physical assessment of the donor, and also tissue matching, such as whether the blood type between the couple is the same, etc. Only if the above two conditions are met can the organ transplant be performed.