Hematocrit is generally defined as the erythrocyte sedimentation rate, and 40-60 mm/h is high, which may be physiologically accelerated or pathologically accelerated. The normal erythrocyte sedimentation rate is usually less than 15 mm/h in men and less than 20 mm/h in women, while 40-60 mm/h is higher than the normal range. In the case of infants, young children, menstruation, or pregnancy from the third month to the postpartum period, physiologic acceleration is most often considered. However, in patients with other conditions, it may be pathologically accelerated due to acute inflammation, active rheumatism, anemia, malignancy, active tuberculosis, severe tissue destruction and other diseases. Also, an accelerated erythrocyte sedimentation rate can provide a value for malignant tumors, which usually slows down in patients after surgical resection or effective treatment such as radiotherapy. The value may also increase if the tumor recurs or metastasizes. If the erythrocyte sedimentation rate is 40-60 mm/h, it is recommended to consult a doctor to find out the cause of the disease and to actively carry out targeted treatment.