Colchicine’s is mainly used clinically for the treatment of gout and it is also an anti-malignant drug. Its side effects include digestive impairment, renal damage, bone marrow suppression and so on. 1. Digestive impairment: colchicine may stimulate the mucous membrane of the digestive tract, manifested as nausea, vomiting, diarrhea, abdominal pain and other gastrointestinal reactions, hepatocellular damage may appear jaundice and other symptoms, symptoms should be stopped immediately and promptly go to the hospital for treatment. 2. Kidney damage: proteinuria may occur, but rarely cause renal failure. 3. Bone marrow suppression: may cause blood system damage, such as granulocytopenia. If the above side effects occur, the patient should stop taking the medicine immediately and seek medical treatment in time to take appropriate therapeutic measures.