There is no go melanin precipitation the most effective drugs, can choose to use vitamin C-rich ointment, vitamin E ointment, hydroquinone cream and other ointments, the specific efficacy of individual differences, can be under the guidance of the doctor, a reasonable choice. 1. Vitamin C-rich ointment: Vitamin C has a strong antioxidant effect to lighten the effect of melanin. 2. Vitamin E ointment: it has moisturizing and antioxidant effects, and can also help lighten melanin. 3. Hydroquinone cream: Hydroquinone cream is a reducing agent, antioxidant, reducing effect, can prevent the production of melanin, in order to achieve the effect of removing melanin. Normally, we should pay attention to good sunscreen to prevent ultraviolet radiation, to prevent the aggravation of color deposition, creams need to be used under the guidance of a doctor, if necessary, can be combined with physical therapy, such as intense pulsed light and so on.