Elevated serum lipase is indicative of certain diseases and can be categorized into pancreatic and non-pancreatic diseases. 1. Pancreatic diseases: elevated serum lipase is common in pancreatic diseases, especially acute pancreatitis. It starts to rise around 4~8h after the onset of acute pancreatitis and reaches the peak around 24h, and the degree of elevation is positively correlated with the severity of pancreatitis. In addition, serum lipase also increases to a certain extent in chronic pancreatitis, but to a lesser extent than in acute pancreatitis. 2. Non-pancreatic diseases: common in peptic ulcer perforation, acute cholecystitis, intestinal obstruction and other acute abdomen. For those who have elevated serum lipase, they need to consult a doctor in time to find the cause of the disease, so as to avoid delaying the treatment and causing adverse effects on the body.