Alopecia areata is a common disease with complex etiology and pathogenesis, which is very difficult to treat and requires more than 6 months of treatment before significant results can be seen. Alopecia areata is divided into physiological alopecia and pathological alopecia, like seasonal alopecia, malnutrition alopecia and other physiological alopecia can be self-healing, pathological alopecia is divided into non-scarring alopecia (androgenic alopecia, baldness) and scarring alopecia (such as hair flatulence, scalp discoid lupus erythematosus), the former can be partially recovered, the latter to prevent the aggravation of the disease. 1, about the efficacy: hair loss is a refractory disease, but also a slow treatment process, due to a variety of causes, the efficacy also varies, first of all, we recommend that you do not be too nervous, anxious, if the hair loss situation, should go to the regular hospital dermatology or hair specialist as soon as possible. At present, domestic experts jointly advocate early, long-term, standardized, combined and individualized treatment, if the treatment goes well, generally 3 months to stop the loss, 6 months may see obvious results. The hair loss is all degenerated hair follicles and will not grow thick and long, only the new hair may grow thick and long. Scarring alopecia, creeping baldness, congenital hypotrichosis, severe androgenic baldness and some severe baldness are less effective. 2, about the phenomenon of wild hair loss: In the early stage of treatment, because some of the resting or already damaged hair follicles stop growing, this part of the hair is gradually shed after medication and re-enter the anagen phase, so the hair loss increases, do not worry, generally 6-12 weeks will gradually ease. In fact, hair has always been in the shedding and growth to maintain a dynamic balance, if the growth rate shedding rate, the total amount of hair will increase, the opposite will be reduced, the purpose of treatment is to promote growth and reduce shedding. 3.On the issue of relapse: As hair loss is a refractory disease, the prognosis is different for different hair loss types. Patients with androgenic baldness will relapse, and the degree of hair loss will return to the starting point after stopping treatment for a period of time. Long-term maintenance treatment is required, at least one of oral or topical application should be chosen. Mild baldness can be self-healing. Severe baldness with more than 50% hair loss area has the possibility of relapse after stopping the medication and needs to be maintained by reducing the dosage or reducing the medication.