Dryness, or dry syndrome, is improved by standardized medication, appropriate alternative treatments, and lifestyle adjustments, which are effective in relieving the patient’s symptoms and improving the patient’s condition. Dry syndrome, also known as Sjögren’s syndrome, is a diffuse connective tissue disease that mainly damages the exocrine glands of the human body. The treatment of this disease is mainly based on medication, and the commonly used medications include non-steroidal anti-inflammatory drugs such as indomethacin and ibuprofen, glucocorticosteroids such as prednisone and dexamethasone, and immunosuppressive agents such as methotrexate. In addition to medication, patients with dry syndrome can also use artificial tears, artificial saliva and other alternative treatments to relieve local symptoms. In life, we should pay attention to drink more water, quit smoking, alcohol, keep the mouth clean, rinse frequently to prevent dental caries and infection, pay attention to eye hygiene, avoid taking drugs that may cause dry mouth. The above drugs should be used under the guidance of a physician, and it is recommended that patients with dry syndrome go to the rheumatology and immunology department of a regular hospital for detailed consultation.