A lot of red bumps on the thighs consider the following possibilities: 1, erythema nodosum, mainly due to inflammation around the blood vessels and vasculitis, the rash can appear deep in the nodules, bumps, surrounded by the performance of erythema, there is a certain amount of pressure pain, tenderness. In clinical treatment, oral glucocorticoids such as methylprednisolone tablets, prednisone acetate tablets, topical glucocorticoid ointment such as mometasone furoate ointment, fluticasone propionate ointment; 2, consider papular urticaria, mainly due to insect bites caused by staying in the field allergic reactions, in clinical treatment can be oral levocetirizine hydrochloride oral solution, topical fluticasone propionate cream 1 time/day application treatment The clinical treatment can be oral levocetirizine hydrochloride and topical fluticasone propionate cream once/day.