There are several common causes of itchy bone: 1. Inflammation around the bone, including periostitis, fasciitis, and ligament inflammation, due to the infiltration of inflammatory cells causing increased local nerve tension, resulting in irritation of sensory nerves with irritation symptoms, mild irritation symptoms will manifest as itchy symptoms, and in severe cases, pain. 2. seen in poor blood circulation around the bone, resulting in local tissue 3. It can be seen in bone tumors, where the growth of bone masses leads to stimulation and lifting of the periosteum. In malignant bone tumors, due to the rapid growth and aggressive growth of tumors, they often show painful symptoms.