Long-term non-healing of skin wounds in the thin fat area in front of the tibia may be caused by slow metabolism, wound infection or diabetes, etc. It is necessary to take targeted medication, nutritional support, treatment of the original disease and other treatments. 1. Medication: Most of the long-term non-healing wounds are associated with secondary infections, which need to be treated with antibiotics as prescribed by the doctor, such as erythromycin and azithromycin, and the wound site should be kept clean, with regular dressing changes and localized use of antibiotics. 2. Nutritional support: Due to the weakness of tibial fat and muscle tissue, the nutritional status is poor, which can easily lead to non-healing wounds, therefore, attention should be paid to dietary supplementation, eat more food rich in protein, vitamins, etc., eat more fresh vegetables and fruits, and appropriate functional exercise to promote wound healing. 3. Treatment of primary disease: If patients with diabetes, due to high blood sugar content in the body, often lead to slow wound healing, should actively cooperate with the doctor to control blood sugar, to reduce the impact of high blood sugar on the wound, to promote wound healing. If the fat in front of the tibia is very thin skin wounds do not heal for a long time, you should go to the hospital in time to review, under the guidance of the doctor to carry out targeted treatment, if necessary, may also need to carry out surgical treatment.