Treatment of penile atrophy caused by diabetes mellitus can be carried out by controlling blood glucose and applying nutritive nerve drugs (such as methylcobalamin) and circulatory improvement drugs (such as sildenafil) as prescribed by the doctor. 1. Blood glucose control: blood glucose should be controlled actively, with fasting blood glucose below 7.0mmol/L and postprandial blood glucose below 10mmol/L, which can slow down the condition and control the occurrence and progress of complications. 2. Nutritional nerve: penile atrophy caused by diabetes mellitus suggests that diabetic autonomic nerves may have lesions, and can be treated with methylcobalamin, epalrestat and other nutritional nerve therapy as prescribed by the doctor. 3. Improve circulation: Diabetes-induced penile atrophy may be related to vascular sclerosis and occlusion, which can be treated with medications to improve circulation, such as sildenafil, under the guidance of a doctor. If you have diabetes-induced penile atrophy, it is recommended that you consult a doctor and follow the doctor’s instructions.