Yellowing of the whole body is not necessarily a sign of cancer, it is mostly seen as a symptom of generalized jaundice caused by hemolysis and other factors and should not be generalized. Yellowing of the whole body is jaundice. An increase in the concentration of bilirubin in the blood due to various reasons may cause yellowing of the sclera, mucous membranes, skin and body fluids. There are many causes of systemic jaundice, which can be seen in hemolysis, cholestasis, and liver cell injury, such as viral hepatitis, cirrhosis, hemolytic anemia, gallstones, and biliary ascariasis. In addition, pancreatic head cancer and hepatocellular carcinoma can also lead to the manifestation of yellowing of the whole body, which needs to be paid great attention. Therefore, it is recommended that patients should visit the gastroenterology department of the hospital in time, and the specific situation can be confirmed through ultrasound, CT and other imaging examinations, as well as regular health checkups. Once the symptoms associated with early stage of cancer, further examination and treatment are needed.