Systemic lupus erythematosus is a common autoimmune disease that mostly affects young women of childbearing age. Many women with lupus are told by their doctors that pregnancy is not recommended during the treatment process, and the desire to be a mother makes these patients repeatedly ask the question: Is it true that lupus patients cannot get pregnant? SLE itself does not affect pregnancy, it is some medications used during the treatment process and the woman’s own physical condition that restrict the safety of pregnancy. Therefore, if the right timing is chosen, lupus patients can give birth to their babies with certain medical protection. There are two main reasons why pregnancy was not recommended for lupus patients in the past: first, the medications used in the treatment of lupus are not good for the child, such as high doses of hormones and some immune preparations. If the patient still needs to rely on medications to maintain a normal life, it is obviously not appropriate to get pregnant. Secondly, the diverse manifestations of lupus and the possible organ damage in many patients also do not suggest pregnancy. “Many patients are now more stable, with no more erythema, no more mouth ulcers, and no more joint pain. If some more laboratory tests are performed to determine that the indicators are okay. Pregnancy can usually be considered for those who have been off medication for more than a year.” Another important condition for a successful pregnancy in lupus patients is to have a strong obstetrics department as a guarantee. “For example, if some patients have a sudden drop in platelets during pregnancy, generally the pregnancy can only be terminated by abortion. But if there is a good obstetrics department that can deal with various situations such as less than term delivery, we are confident to treat the patient. We have had some lupus patients give birth to babies before without any problems.”