Gammopathy, or erythrocyte glucose-6-phosphate dehydrogenase deficiency, does not have a few years of age to enter a safe period for this disease. Lifelong attention to medications and dietary factors is needed to avoid causing hemolysis. Erythrocyte glucose-6-phosphate dehydrogenase deficiency is a hereditary disease that cannot be completely cured. Eating foods such as fava beans or drugs such as sulfonamides may cause hemolytic anemia, which manifests itself as malaise, fever, dizziness, anorexia, vomiting, abdominal pain, mild yellow staining of the sclera, and urine that looks like strong black tea or soy sauce. Therefore there is no such thing as what age to enter the safe period. In patients with this disease, lifelong attention is required to avoid the use of anti-malarial drugs (e.g. quinine), antipyretics (e.g. aminopyralid), sulfonamides, etc., as well as the contraindication of fava beans, so as to avoid inducing the occurrence of hemolysis. Specific diagnosis and treatment should be carried out under the supervision of a physician.