The presence of abnormal sperm in normal male semen is normal if the percentage of head defective sperm is less than 30%. Once the deformity rate is higher than 50%, it is clinically known as high deformity rate. A high sperm deformity rate has a great possibility of causing infertility. The deformity of sperm is caused by epididymal tuberculosis, mumps, varicocele and diseases of the urogenital system. For organisms taking long-term anti-cancer drugs as well as drugs such as reserpine and Marilan, which can easily lead to sperm malformation, it is recommended to take good local hygienic care in daily life, keep the local area clean and clear, and avoid inflammation. In daily life to develop good habits, bad habits are the main cause of sperm deformities, avoid smoking and drinking, which nicotine and alcohol will have a certain killing effect on sperm, long-term smoking and drinking can easily lead to infertility.