Whether or not the uric acid medicine should be taken for a long time needs to be decided according to the patient’s uric acid situation after stopping the uric acid medicine and the patient’s underlying disease, and cannot be generalized. 1. The uric acid situation after stopping uric acid-lowering drugs: if the patient can maintain the uric acid below 360 μmol/L after stopping uric acid-lowering drugs, long-term medication is not required; if the uric acid cannot be maintained below 360 μmol/L after stopping uric acid-lowering drugs, long-term medication is required. 2. Underlying diseases: If there are recurrent gout, renal failure and diabetes and other cardiovascular diseases, most of these cases require long-term treatment with uric acid-lowering drugs. Patients with high uric acid are advised to consult a doctor in a timely manner, according to their own conditions under the guidance of a physician to standardize the treatment, if the condition allows to stop the drug, should be under the guidance of a physician before stopping the drug, do not stop the drug on their own.