The ultrasound presentation of triple-negative breast cancer is dominated by hard tumors with indistinct borders and burr-like lesions. Calcification may appear in the lesion, and it is also accompanied by abundant blood flow signals. It should be noted that the ultrasound presentation of triple-negative breast cancer or other types of breast cancer is basically the same. It is not possible to distinguish triple-negative breast cancer from other types of breast cancer by ultrasound examination. Pathologic examination, immunohistochemistry, genetic examination, etc. are needed to distinguish different types of breast cancer. Clinically, by categorizing breast cancer, the patient’s condition can be further clarified. Different chemotherapy, radiotherapy and targeted therapy programs can be adopted according to the specific classification. It is recommended that breast cancer patients seek medical treatment in time and follow the doctor’s instructions to avoid delaying their condition.