Adrenocorticotropic hormone, or adrenocorticotropic hormone, acts primarily in the adrenal cortex. Adrenocorticotropic hormone is generally released mainly by the pituitary gland and is a peptide hormone, and a few tumors can also release this hormone. It mainly acts on the adrenal cortex, which can promote the proliferation of adrenal cortical tissues and the production and secretion of corticosteroid, so adrenocorticotropic hormone affects adrenal secretion function. When adrenocorticotropic hormone increases, it can be seen in pituitary tumors, etc., which in turn leads to excessive secretion of glucocorticoids by the adrenal glands, causing Cushing’s disease, which manifests itself in symptoms such as centripetal obesity, full-moon face, and high blood pressure. When the adrenocorticotropic hormone is reduced, it can be seen in the pituitary function decline, pituitary gland damage, etc., which can cause lead to the adrenal glands to secrete insufficient glucocorticoids, causing generalized fatigue, loss of appetite, weight loss and other symptoms. When adrenocorticotropic hormone secretion abnormality occurs, it is recommended to consult a doctor in time to clarify the cause of the disease and standardize the treatment.