Cranial repair surgery is a routine procedure in neurosurgery, which is a surgical procedure that involves repairing the defective area of the skull using certain materials to reconstruct a complete and closed cranial cavity for a variety of causes of cranial defects. This surgery is very old and classic, and the technique is now very sophisticated. One of the most important aspects of cranial repair is the material used. Over time, the materials used in cranial bone repair have been revolutionized, becoming more and more advanced and better and better. Currently, titanium mesh is the most widely used material in clinical practice. Some patients ask whether titanium mesh cranial bone can be lifelong? In fact, as far as the material itself is concerned, titanium mesh is a kind of metal alloy material, its durability is possible, theoretically it can be completely lifelong. However, there are always accidents, and although titanium mesh is an improvement over previous materials (such as plexiglass, calcium phosphate bone cement, hydroxyapatite, etc.), there are still problems. For example, titanium mesh cranial bone repair, there are cases of rejection, infection, etc.; titanium mesh covered repair, its sharp edges wear the scalp phenomenon, and even cause scalp breakage, material exposure; titanium mesh hardness is not strong enough, may be deformed and collapsed by the external force, etc., and affect the CT nuclear magnetic examination, the hot and cold environment sensitive to a number of problems. Therefore, there are many patients who have to replace the material after titanium mesh skull repair fails. So for cranial bone repair surgery, we must carefully choose the repair material. Polyetheretherketone PEEK is a new material with excellent performance, very close to the autologous skull, with good feedback in clinical use. Although titanium mesh cranium can theoretically be used for a lifetime, but in practice there may be such and such problems. Therefore, patients should be careful when choosing the repair material, and choose the material that is similar to the autologous skull to repair the skull.