Metformin extended-release tablets are not recommended to be taken at night before bedtime, and are recommended to be taken with or after meals. Metformin extended-release tablets belong to the class of biguanide glucose-lowering drugs, which can be used to treat patients with type 2 diabetes mellitus who are unable to control their blood glucose well by diet and exercise alone. It should be noted that this drug should not be used in people who are allergic to this product, severe kidney failure, heart failure, respiratory failure, serious infection, trauma and so on. Because nausea, vomiting, abdominal pain and other gastrointestinal adverse reactions may occur after Metformin Extended-Release Tablets, patients who need to take Metformin Extended-Release Tablets are advised to take them after a meal to help reduce gastrointestinal reactions. Patients who need to take metformin extended-release tablets should be used under the guidance of a doctor, and should not blindly use the drug on their own.