Motion sickness generally refers to motion sickness, there is no so-called “most effective” drugs, should be depending on the specific symptoms of targeted medication, commonly used antihistamines such as phenylephrine, anticholinergic drugs such as scopolamine. Motion sickness is a series of physiological reactions to the wrong perception of the motion state, such as dizziness, headache, nausea, vomiting, pallor, etc., that is, people often say “motion sickness”, “seasickness”, “airsickness “. There is no so-called “most effective” drug for the treatment of motion sickness. Antihistamines such as diphenhydramine, theobromine and promethazine can be taken, as well as anticholinergics such as scopolamine tablets. It can be taken before taking transportation to prevent the discomfort caused by motion sickness. In addition scopolamine is also available in patch form, which can be applied behind the ear. The above medications are recommended to be used under medical supervision. In addition to medication, motion sickness can also be improved through behavioral improvements, such as choosing the front seat of the car when taking transportation, avoiding close reading or watching screens, looking into distant horizons, and keeping the head stable.