Higher bilirubin levels can be caused by physiological factors such as diet, or pathologic factors such as diseases of the hepatobiliary system. 1. Physiological factors: If you are usually healthy and do not have any uncomfortable symptoms, and you find that your bilirubin level is high during your health checkup, it may be a normal physiological phenomenon, for example, consuming a large amount of high-fat food or drinking a large amount of alcohol will easily lead to high bilirubin level. 2. Hepatobiliary system diseases: If the bilirubin is significantly elevated, more than three times of the normal value, it may be related to acute viral hepatitis, cholestatic hepatitis, bile duct stones, cirrhosis, liver cancer, pancreatic cancer, etc., which will affect the excretion of bile and lead to the elevation of bilirubin. If the test result of bilirubin is high, it is recommended to go to the regular hospital for consultation, after clarifying the cause of the disease, and then carry out targeted treatment or therapy under the guidance of the doctor.