There is no optimal treatment for infant drool rash. Generally, infant drool rash can be treated by timely cleaning of the affected skin and appropriate use of some anti-inflammatory drugs such as erythromycin ointment. Infantile Drool Rash is more often seen in infants around 6 months old, which is a kind of skin inflammation caused by saliva long-term stimulation of the skin at the corners of the mouth, manifested as papules, macules, pimples, severe redness, ulcers, infections, and other symptoms of the skin around the mouth and face. It can be treated with anti-inflammatory drugs such as erythromycin ointment under doctor’s supervision. When babies with drool rash, parents should pay attention to strict care to minimize the saliva contact with the baby’s skin, but need to avoid repeated use of wet paper towels, easy to destroy the skin barrier, contact with saliva may cause a vicious cycle. You can put a suitable bib on the baby, try to use a clean and soft towel to wipe off the drool in time, and replenish the baby’s moisturizer in time. If the symptoms of drool rash are not relieved or accompanied by other symptoms, you should go to the hospital in a timely manner to give targeted treatment after the cause is clear, and at the same time pay attention to the use of drugs need to follow the doctor’s instructions, do not self-medication.