Itchy legs after drinking may be caused by alcohol allergy, cholinergic urticaria, acute eczema and other diseases. 1. Alcohol allergy: alcohol allergy may be the body is allergic to alcohol. Patients may have erythema, papules, itching and other symptoms of the skin, so it may be manifested as itching legs after drinking. 2. Cholinergic urticaria: Cholinergic urticaria may be induced by drinking, exercise, hot weather and other factors. Mainly manifested in the symptoms, such as wind, itching, etc., when the patient can induce cholinergic urticaria after drinking alcohol, occurring in the legs can appear leg itching. 3. Acute eczema: Acute eczema may be triggered by long-term alcoholism, long-term irregular life, intake of irritating substances, nervous tension and other factors. If acute eczema is induced or aggravated after drinking alcohol, itching of legs, red spots, pimples and other symptoms may appear. There are many reasons that lead to itchy legs after drinking, and it is recommended that patients go to regular hospitals in time to find out the cause of the disease and timely treatment.