Cholera is a virulent intestinal infection caused by the bacterium Vibrio cholerae, which is transmitted through contaminated water or food. The main sources of cholera are patients and carriers, whose vomit and diarrhea may contain large amounts of Vibrio cholerae. Water and food contaminated with Vibrio cholerae can cause cholera epidemics, and indirect transmission is also caused by daily contact and flies. In addition, Vibrio cholerae can spread through contaminated shrimp, fish and other aquatic products. In our country, cholera epidemic season is summer and fall, the epidemic area is mainly along the coast, for our country class A infectious disease, manifested as the onset of acute, diarrhea, accompanied by vomiting. If cholera occurs, it should be admitted to the hospital in time, strictly isolated, timely rehydration, and treated under the guidance of doctors.