There are several reasons why you wake up feeling pain on both sides of your buttocks, and a common reason may be a strained buttock muscle. This is mainly due to the fact that a lot of exercise before going to bed, such as frequent squatting or weight lifting and other exercises can strain the buttock muscles. When the gluteal muscles are injured, this injury will manifest itself through a period of rest. This is manifested by waking up with pain on both sides of the buttocks. The cause of this phenomenon can also be due to colds and other diseases. Because colds and other illnesses can lead to muscle aches and pains all over the body, it is normal for pain to appear on both sides of the buttocks as well. Also, waking up with pain on both sides of the buttocks may be related to the sleeping position and the unsuitability of the bed. For example, thin and weak people, if the bed is too hard or the bed is not made flat, it will cause the buttocks to squeeze and lead to pain on both sides of the buttocks after a night’s sleep. This can be improved by adjusting the sleeping position and the bed.