Once the skin itches at night, first of all, avoid prohibiting spicy and stimulating food, avoid excessive washing, rubbing, avoiding high water temperature when washing, and using less detergents. You can also use topical cooling and anti-itching herbal preparations, such as compound camphor cream, dampicol ointment, etc., or weak glucocorticoid preparations, such as dexamethasone acetate cream, hydrocortisone cream, dinaide cream, etc. Oral antihistamines such as levocetirizine, azelastine, fexofenadine, chlorpheniramine, loratadine, epinastine, etc., or herbal preparations such as moistening and anti-itching capsules can also be taken. In addition, chronic intractable itching requires exclusion of medical diseases such as diabetes mellitus and chronic kidney disease.